New ML Program Can Characterise Single Cell RNA-seq
New ML Program Can Characterise Single Cell RNA-seq
New ML Program Can Characterise Single Cell RNA-seq
Neural networks and supervised machine learning (ML) techniques can characterise cells studied using single cell RNA-sequencing (scRNA-seq), scientists from Carnegie Mellon University (CMU) have learnt. This could aid others in identifying new cell subtypes and in discerning diseased cells.
New ML Program Can Characterise Single Cell RNA-seq
Defective DNA Repair Leads to Genome "Chaos"
Defective DNA Repair Leads to Genome "Chaos"
Defective DNA Repair Leads to Genome "Chaos"
Scientists have found a cause for the frequent and damaging events in cancer cells’ genetic material where sections of individual chromosomes were broken at a number of points and reassembled wrongly, so entire sections were missing and others were duplicated or incorporated in a wrong orientation.
Defective DNA Repair Leads to Genome "Chaos"
Single Cell Applications – The Present and The Future
Single Cell Applications – The Present and The Future
Single Cell Applications – The Present and The Future
Microfluidics for use in single cell applications is growing in popularity, as scientists are taking advantage of increasing numbers of commercially available systems enabling high throughput analysis of single cells.
Single Cell Applications – The Present and The Future
CRISPR Repairs DNA Even Without Donor Template
CRISPR Repairs DNA Even Without Donor Template
CRISPR Repairs DNA Even Without Donor Template
CRISPR-Cas9 can carry out precise genome editing even without the assistance of donor DNA templates, a team of scientists from Brigham and Women’s Hospital and the Broad Institute of MIT and Harvard have found.
CRISPR Repairs DNA Even Without Donor Template
New Tech Predicts Biosequence Binding in Seconds
New Tech Predicts Biosequence Binding in Seconds
New Tech Predicts Biosequence Binding in Seconds
A new technology known as “Pattern to Knowledge” (P2K) has been created by researchers at the University of Waterloo to predict the binding of biosequences in only seconds. The new development could radically speed up discovery of new drugs and reduce the need for expensive laboratory tests.
New Tech Predicts Biosequence Binding in Seconds

Breaking News

New ML Program Can Characterise Single Cell RNA-seq

Neural networks and supervised machine learning (ML) techniques can characterise cells studied using single cell RNA-sequencing (scRNA-seq), scientists from Carnegie Mellon University (CMU) have learnt. This could aid others in identifying new cell subtypes and in discerning diseased cells.

Defective DNA Repair Leads to Genome “Chaos”

Scientists have found a cause for the frequent and damaging events in cancer cells’ genetic material where sections of individual chromosomes were broken at a number of points and reassembled wrongly, so entire sections were missing and others were duplicated or incorporated in a wrong orientation.

CRISPR Repairs DNA Even Without Donor Template

CRISPR-Cas9 can carry out precise genome editing even without the assistance of donor DNA templates, a team of scientists from Brigham and Women’s Hospital and the Broad Institute of MIT and Harvard have found.

New Tech Predicts Biosequence Binding in Seconds

A new technology known as “Pattern to Knowledge” (P2K) has been created by researchers at the University of Waterloo to predict the binding of biosequences in only seconds. The new development could radically speed up discovery of new drugs and reduce the need for expensive laboratory tests.

Mutations in “Guardian of the Genome” Assist Cancer in Spreading

Tumours are helped in their development by mutating the most important cancer-prevention gene, p53, scientists from Melbourne have found. The study, published in Genes and Development, found that mutant p53 prevents the regular p53 protein from activating its natural defences, increasing the risk of the cancer spreading.

Magazines and Educational Guides

Sequencing Buyers’ Guide

The development of the first automated DNA sequencers completely revolutionized the field of DNA sequencing and, eventually, made it possible to publish the first draft sequences of the human genome. Since then, a whole host of companies have developed their own approaches to DNA sequencing, resulting in a market that is filled with different possibilities […]

Molecular Diagnostics Report

Read our report on all things Molecular Diagnostics, including some great contributed articles. Need to know about liquid biopsies? Want to know what the current regulatory landscape looks like? Then you’ve come to the right place.

Gene Editing 101: 2018 Edition

Free download: This guide will discuss the gene editing tools currently available and how they can be used to manipulate genomic sequences, as well as the real world applications that put these tools to use.

The Genome Spot / Webinars

Maize genome complexity traversed with Oxford Nanopore technology

  Maize is one of the most economically important crops globally and much effort has been spent generating the high quality B73 reference genome. However, the 10 chromosome, 2.3 gigabase (Gb) B73 reference genome was a substantial challenge due to the fact it is comprised of 85% transposable elements, 75% of which are long terminal […]

Human genome sequencing on PromethION: characterization of structural variants and repetitive regions

  At the VIB-UAntwerp Center for Molecular Neurology, we apply sequencing technologies to elucidate the genetic etiology of neurodegenerative brain diseases such as Alzheimer Disease and Frontotemporal Dementia. Structural variation and repetitive regions are insufficiently characterized using currently dominant short-read sequencing technologies. Long-read sequencing on the Oxford Nanopore PromethION has the potential for a comprehensive […]

Opinions

GWAS Coming Of Age

There’s a fantastic editorial over in nature medicine that you should really take a look at, if you’re interested in finding out more about where the future of GWAS might be heading.

Educate Yourself

Making Pregnancy Safer

Non-Invasive Pre-Natal Testing (NIPT) has the potential of bringing safer pregnancy testing to the wider NHS, but not without its challenges.

65 Years of DNA

Happy DNA Day! To celebrate, we’ve put together a timeline of some of the major events that have happened in genomics since 1953 – See how far we’ve come!

Front Line Genomics Exclusives

Around the Web

Blog

Weekend Reads

This week: Are the conclusion about ‘alien’ mummy, Ata correct? Where is the African DNA in the search for cures? And is it possible to bury family secrets in the age of DNA testing? 

Weekend Reads

This week: Are we really running out of data storage? And can a deadly infection be genetic? You’ll also get a list of must-reads this summer… 

Weekend Reads

This week: Reversed ageing, pig organs, the future of humankind and citizen scientists using genetics to solve past crimes.